Author

Bryan T. Phillips

University of IowaORCID 0000-0002-4154-1714Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:C. elegans· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Albert J. ErivesiD· 1 shared Amanda N. D. AdamsiD· 1 shared Arielle Koonyee-Lam Wolf· 1 shared Kimberly N. BekasiD· 1 shared Lori C. Adams-PhillipsiD· 1 shared Maria F. Valdes Michel· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 6 mutual co-author links

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1 shared paperDevelopmental Biology

Albert J. ErivesORCID

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3 papers

Recent·Most cited

Developmental BiologyCells & DevelopmentPeer-reviewedJun 1, 2025

Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizations

Arielle Koonyee-Lam Wolf, Lori C. Adams-Phillips, Amanda N. D. Adams…·Bryan T. Phillips

This study investigates the evolution of beta-catenin paralogs in C. elegans, showing that SYS-1 compensates for missing domains through novel transactivation and nuclear localization mechanisms.

1 citation

C. elegansexperimental assay

𝕏 PostBluesky

Developmental BiologyMolecular Biology of the CellPeer-reviewedJan 15, 2025

SYS-1/beta-catenin inheritance and regulation by Wnt-signaling during asymmetric cell division.

Maria F. Valdes Michel, Bryan T. Phillips

The paper quantifies SYS-1 inheritance during asymmetric cell division in C. elegans and shows its regulation by centrosomal processing and Wnt signaling in both mother and daughter cells.

DOI 10.1091/mbc.e24-10-0441

C. elegansexperimental assay

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJan 10, 2022

unc-37/Groucho and lsy-22/AES repress Wnt target genes in C. elegans asymmetric cell divisions

Kimberly N. Bekas, Bryan T. Phillips

This study shows Groucho and LSY-22/AES repress Wnt target genes in C. elegans asymmetric cell divisions, with Groucho regulating POP-1/TCF expression and LSY-22/AES acting as a TCF repressor.

8 citations

C. elegansexperimental assay

𝕏 PostBluesky