Developmental BiologyCells & DevelopmentPeer-reviewed
Nuclear localization and transactivation of SYS-1/β-catenin is the result of serial gene duplications and subfunctionalizations
Arielle Koonyee-Lam Wolf, Lori C. Adams-Phillips, Amanda N. D. Adams…·Bryan T. Phillips
This study investigates the evolution of beta-catenin paralogs in C. elegans, showing that SYS-1 compensates for missing domains through novel transactivation and nuclear localization mechanisms.