Zicheng Hu

The paper introduces the Immunogenicity Database (IDC) to standardize and integrate clinical immunogenicity data, highlighting trends in anti-drug antibody incidence and risk factors.

The paper measures CSF proteins in HIV-1 infected and uninfected individuals, identifying patterns of protein changes associated with CNS injury and treatment effects.

The paper identifies a novel plasmacytoid dendritic cell lineage in mice and humans derived from common lymphoid progenitors, characterized by unique gene expression and functional properties.

The paper evaluates druggable genes in mice and finds that many understudied ones have significant phenotypes similar to human diseases, suggesting therapeutic potential.

This paper introduces a deep learning model for cytometry data that accurately diagnoses latent CMV infection and identifies associated cell populations.

MetaCyto enables meta-analysis of flow and mass cytometry data, revealing racial differences in immune cell populations across 2926 samples.

xCell infers 64 immune and stroma cell types from transcriptomes using gene-signature-based methods and outperforms existing approaches in in silico analyses.