Author

Kevin W. Trotter

National Institute of Environmental Health SciencesORCID 0000-0002-4182-9523Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Trevor ArcheriD· 2 shared Eric J. MillimaniD· 1 shared Jackson A. HoffmaniD· 1 shared James M. WardiD· 1 shared Leesa J. DeterdingiD· 1 shared Nolan G. GokeyiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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2 shared papersGenomics

Trevor ArcherORCID

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2 papers

Recent·Most cited

The Loss of the H1.4 Linker Histone Impacts Nascent Transcription and Chromatin Accessibility

Nolan G. Gokey, James M. Ward, Eric J. Milliman, Leesa J. Deterding, Kevin W. Trotter, Trevor Archer

The paper shows that loss of H1.4 linker histone affects chromatin accessibility, histone modifications, and gene expression, particularly impacting stress response pathways and immune-related genes.

iScience · Aug 22, 2025Peer-reviewedGenomics

RNA Polymerase II coordinates histone deacetylation at active promoters

Jackson A. Hoffman, Kevin W. Trotter, Trevor Archer

The paper shows that transcription initiation is not required for histone acetylation and H2AZ incorporation at TSSs but limits their maintenance.

Science Advances · Feb 5, 2025Peer-reviewedMolecular Biology