Molecular BiologybioRxivPreprint
ACE2-independent sarbecovirus cell entry is supported by TMPRSS2-related enzymes and reduces sensitivity to antibody-mediated neutralization
Lu Zhang, Hsiu-Hsin Cheng, Nadine Krüger…·Markus Hoffmann
This study identifies an ACE2-independent pathway for sarbecovirus entry in human cells, mediated by TMPRSS2-related proteases and linked to reduced antibody neutralization.
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