Lu Zhang

The paper characterizes the epidemiology and virology of the SARS-CoV-2 variant PJ.2.1, finding it spreads mainly in older adults and shows increased ACE2 binding but not greater antibody evasion.

This study shows the QTQTX motif in BA.3.2 S protein is not required for cleavage or lung cell entry, which depends on TMPRSS2 instead.

This paper identifies Sec61β as essential for proteolytic processing and cell entry of Marburg virus glycoprotein, unlike Ebola virus, and suggests Sec61 as a therapeutic target.

This study investigates the virological traits of the SARS-CoV-2 BA.2.87.1 lineage, finding it efficiently enters human cells but is more sensitive to antibody neutralization than JN.1.

This study identifies an ACE2-independent pathway for sarbecovirus entry in human cells, mediated by TMPRSS2-related proteases and linked to reduced antibody neutralization.

The paper shows that SARS-CoV-2 mutations from mink reduce antibody neutralization, suggesting potential risks for human infections.