Hiromichi Matsugo

This study compares how Oz virus and Dhori virus polymerases regulate RNA synthesis across genome segments using minigenome systems, revealing differences in promoter activity based on distal duplex sequence variations.

This study establishes a reverse genetics system to recover infectious Oz virus from cloned cDNA, demonstrating efficient viral replication comparable to wild-type.

The paper develops a minigenome assay to study Oz virus RNA synthesis and finds that Segment 5 has lower promoter activity due to a partial lack of the distal duplex structure.