Author

Deepa K. Murugesh

Lawrence Livermore National LaboratoryORCID 0000-0002-4232-8480Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Assay:scRNA-seq· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

Dina R. WeilhammeriD· 3 shared Margarita V. RangeliD· 3 shared Aimy SebastianiD· 2 shared Ashlee M. PhillipsiD· 2 shared Gabriela G. LootsiD· 2 shared Katrina K. HoyeriD· 2 shared Monica E. GrahamiD· 2 shared Monica K. BoruckiiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersImmunology

Dina R. WeilhammerORCID

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Author profile →

4 papers

Recent·Most cited

A Selenium-Deficient Mouse Model of Mouse-Adapted SARS-CoV-2 Demonstrates Variant Emergence Observed in SARS-CoV-2 Pandemic Variants

Monica E. Graham, Olukunle Oluwapamilerin Oluwasemowo, Deepa K. Murugesh, Margarita V. Rangel, Jeffrey A. Kimbrel, Aram Avila-Herrera, James B. Thissen, Adam T Zemla, Ashlee M. Phillips, Nicole M. Collette, Dina R. Weilhammer, Monica K. Borucki

This study shows selenium deficiency in mice increases viral mutation diversity and generates mutations seen in SARS-CoV-2 pandemic variants.

bioRxiv · Aug 26, 2026 · PreprintMicrobiology

Early immune response to Coccidioides is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation

Nadia Esmeralda Miranda, Oscar A. Davalos, Aimy Sebastian, Margarita V. Rangel, Nicole F. Leon, Bria M. Gorman, Deepa K. Murugesh, Nicholas R. Hum, Gabriela G. Loots, Katrina K. Hoyer, Dina R. Weilhammer

The paper investigates the early immune response to Coccidioides in mice, identifying PD-L1+ neutrophils and Spp1+ macrophages as key players in inflammation and fibrosis.

Microbiology Spectrum · Jul 24, 2025Peer-reviewedImmunology

Improved Zika virus plaque assay using Vero/TMPRSS2 cell line

Olukunle Oluwapamilerin Oluwasemowo, Monica E. Graham, Deepa K. Murugesh, Monica K. Borucki

The paper compares plaque formation of ZIKV strains on Vero and Vero/TMPRSS2 cells, finding that Vero/TMPRSS2 cells produce more visible and distinct plaques.

Microbiology Spectrum · Nov 29, 2024Peer-reviewedMicrobiology

Spatiotemporal Analysis of Lung Immune Dynamics in Lethal Coccidioides posadasii Infection

Oscar A. Davalos, Aimy Sebastian, Nicole F. Leon, Margarita V. Rangel, Nadia Esmeralda Miranda, Deepa K. Murugesh, Ashlee M. Phillips, Katrina K. Hoyer, Nicholas R. Hum, Gabriela G. Loots, Dina R. Weilhammer

This study uses single-cell RNA sequencing and spatial transcriptomics to analyze lung immune responses during lethal Coccidioides infection, identifying macrophages and neutrophils involved in fibrosis and immune dysregulation.

mBio · Nov 29, 2024Peer-reviewedImmunology