Dina R. Weilhammer

A Selenium-Deficient Mouse Model of Mouse-Adapted SARS-CoV-2 Demonstrates Variant Emergence Observed in SARS-CoV-2 Pandemic Variants

This study shows selenium deficiency in mice increases viral mutation diversity and generates mutations seen in SARS-CoV-2 pandemic variants.

Early immune response to Coccidioides is characterized by robust neutrophil and fibrotic macrophage recruitment and differentiation

The paper investigates the early immune response to Coccidioides in mice, identifying PD-L1+ neutrophils and Spp1+ macrophages as key players in inflammation and fibrosis.

Combining computational modeling and experimental library screening to affinity-mature VEEV-neutralizing antibody F5

This paper combines computational modeling and experimental screening to enhance the affinity of the VEEV-neutralizing antibody F5, resulting in variants with significantly improved binding.

Single-cell and spatiotemporal transcriptomic profiling of brain immune infiltration following Venezuelan equine encephalitis virus infection

This study uses single-cell RNA sequencing to analyze immune cell responses in the brain during VEEV infection, identifying distinct subpopulations and spatial patterns of immune infiltration.

Spatiotemporal Analysis of Lung Immune Dynamics in Lethal Coccidioides posadasii Infection

This study uses single-cell RNA sequencing and spatial transcriptomics to analyze lung immune responses during lethal Coccidioides infection, identifying macrophages and neutrophils involved in fibrosis and immune dysregulation.

Cell-free screening, production and animal testing of a STI-related chlamydial major outer membrane protein supported in nanolipoproteins.

The paper develops and tests MOMP-NLP complexes as a potential Chlamydia vaccine using cell-free synthesis and preclinical immunization studies.