Jeffrey S. Davies

The paper shows that PD patients have altered CD4+ T cell responses to fasting/refeeding, leading to impaired neuro-immune signaling through a dysfunctional metabolic program in neurons.

The paper identifies ultra-rare variants in GABAergic genes associated with genetic generalized epilepsy syndromes and links their functional impact to epilepsy severity.

This study shows that GHSRs in the olfactory bulb link hunger to olfactory sensitivity, affecting food-seeking and metabolism in mice.

This study investigates the effects of the 5:2 diet on adult hippocampal neurogenesis and spatial memory in mice, finding no significant impact on neurogenesis or memory performance.

This study shows that acyl-ghrelin reduces dopamine neuron loss and motor deficits in a rat model of Parkinson's disease.

This study uses MRI and histology to identify structural and cellular changes in TDP-43 knock-in mice, linking them to ALS-FTD pathology and identifying PV+ interneuron loss as a potential biomarker.

This paper describes a protocol for quantifying mitochondrial fragmentation in an in-vitro Parkinson's Disease model using cell culture, high-content imaging, and open-source image analysis.

The paper shows that elevated circulating unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is associated with reduced AG:UAG ratio in Parkinson’s disease dementia patients.