Author

Alwena H. Morgan

Swansea UniversityORCID 0000-0002-3441-5357Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

Jeffrey S. DaviesiD· 4 shared Luke D. RobertsiD· 4 shared Daniel J. ReesiD· 2 shared M. Rowan BrowniD· 2 shared Maria Carla Carisi· 2 shared Martina SassiiD· 2 shared Timothy WellsiD· 2 shared Alex ReichenbachiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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4 shared papersNeuroscience

Jeffrey S. DaviesORCID

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4 papers

Recent·Most cited

Aberrant CD4+ T cell refeeding response impairs neuro-immune crosstalk in Parkinson's disease

Karl Austin‐Muttitt, Bethan R David, Martina Sassi, Ravi Agarwal, Thaís S. Sabedot, Jeffrey R. Jones, Michael S. Cuoco, Benjamin J. Jenkins, Luke D. Roberts, Leo Harris, Natalia Kieronczyk, Gang Han, Matthew D. Hitchings, Paul C. Donaghy, Alison Jane Yarnall, , Jeffrey S. Davies

The paper shows that PD patients have altered CD4+ T cell responses to fasting/refeeding, leading to impaired neuro-immune signaling through a dysfunctional metabolic program in neurons.

bioRxiv · May 11, 2026 · PreprintNeuroscience

Acyl ghrelin attenuates neurochemical and motor deficits in the 6OHDA model of Parkinsons disease

Daniel J. Rees, Amy L. Beynon, Mariah J. Lelos, Gaynor Ann Smith, Luke D. Roberts, Lyndsey Phelps, Stephen B. Dunnett, Alwena H. Morgan, M. Rowan Brown, Timothy Wells, Jeffrey S. Davies

This study shows that acyl-ghrelin reduces dopamine neuron loss and motor deficits in a rat model of Parkinson's disease.

Cellular and Molecular Neurobiology · Sep 15, 2022Peer-reviewedNeuroscience

Automated Quantification of Mitochondrial Fragmentation in an In-Vitro Parkinson's Disease Model.

Daniel J. Rees, Luke D. Roberts, Maria Carla Carisi, Alwena H. Morgan, M. Rowan Brown, Jeffrey S. Davies

This paper describes a protocol for quantifying mitochondrial fragmentation in an in-vitro Parkinson's Disease model using cell culture, high-content imaging, and open-source image analysis.

Current Protocols in Neuroscience · Nov 4, 2020Peer-reviewedNeuroscience

Circulating unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is altered in human Parkinson’s disease dementia

Amanda K. E. Hornsby, Luke Buntwal, Maria Carla Carisi, Vanessa Valgas dos Santos, Fionnuala Johnston, Luke D. Roberts, Martina Sassi, Mathieu Méquinion, Romana Stark, Alex Reichenbach, Sarah Haas Lockie, Mario Siervo, Owain W. Howell, Alwena H. Morgan, Timothy Wells, , Jeffrey S. Davies

The paper shows that elevated circulating unacylated-ghrelin impairs hippocampal neurogenesis and memory in mice and is associated with reduced AG:UAG ratio in Parkinson’s disease dementia patients.

Cell Reports Medicine · Oct 1, 2020Peer-reviewedNeuroscience