Sonja Lehtinen

Bacterial strain structure shapes the trajectory of antibiotic resistance genes from plasmid to chromosome

This study shows that bacterial population structure influences the transient dominance of plasmid-borne antibiotic resistance genes over chromosomal integration.

Cluster dispersal shapes microbial diversity during community assembly

The paper investigates how cluster dispersal affects microbial community assembly, showing it promotes homogenization and alters species abundance compared to individual dispersal.

Emergent epistasis mediates the role of negative frequency-dependent selection in bacterial strain structure

This study shows that negative frequency-dependent selection shapes bacterial strain structure through emergent epistasis, using models and genomic analysis of Streptococcus pneumoniae.

Quantifying the effects of antibiotic resistance and within-host competition on strain fitness in Streptococcus pneumoniae

This study quantifies how antibiotic resistance and within-host competition affect pneumococcal strain fitness using longitudinal carriage data.