Anna V Vlasova

The paper shows that different promoter classes use distinct PIC compositions and mechanisms, leading to focused or dispersed transcription initiation patterns in Drosophila.

The paper introduces the EN-TEx resource, which provides personal epigenomes and variant-impact models across multiple tissues, revealing allele-specific loci and their associations with GWAS loci.

The paper identifies and characterizes repressive domains in Drosophila transcription factors using a new high-throughput method, revealing conserved motifs and co-repressor interactions.

The paper identifies five major cell types based on transcriptional programs in human tissues and shows their composition correlates with tissue morphology and disease.

The paper identifies a pan-genome in the Mediterranean mussel with 25% of genes subject to presence/absence variation, suggesting an adaptive strategy for resilience and invasiveness.

The paper estimates the almond genome size and assembly, identifies transposable elements (TEs) as key drivers of divergence between almond and peach genomes, and highlights TE insertions affecting gene expression in traits like kernel taste and mesocarp formation.

The paper predicts SNPs affecting drug-protein binding affinities using genomic and drug interaction data, estimating that individuals carry ~6 SNPs impacting ~5 FDA-approved drugs.