Patrícia O. Prada

This paper develops a genetically encoded sensor, NOPLight, to detect endogenous N/OFQ release with high spatial and temporal resolution in vitro and in vivo.

This study shows that maternal exposure to PM2.5 during pregnancy or lactation increases DNA methylation and reduces expression of Pdx1 and NEUROG3 in mouse pancreatic islets, leading to multigenerational glucose homeostasis issues.