Author

Theodora-Ioana Grosu

University College DublinORCID 0000-0002-4254-831XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CUT&Tag· 1 Assay:Hi-C· 1 Organism:human· 1 Approach:statistical model· 1 Research Focus:transcription & RNA processing· 1

Frequent Co-Authors

Anindita RoyiD· 1 shared Colm J. RyaniD· 1 shared Cosmin TudoseiD· 1 shared Jonathan BondiD· 1 shared Juan M. VaquerizasiD· 1 shared Luke JonesiD· 1 shared Marie-Claire FitzgeraldiD· 1 shared Noura MaziakiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

Anindita RoyORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintAug 28, 2025

Diverse epigenomic mechanisms underpin transcriptional dysregulation in Polycomb-altered acute myeloid leukemia

Cosmin Tudose, Luke Jones, Theodora-Ioana Grosu…·Jonathan Bond

This study investigates how PRC2 depletion in AML affects epigenomic and transcriptional changes, revealing altered chromatin accessibility, H3K27me3 levels, and gene expression patterns that impact cell phenotype and treatment response.

DOI 10.1101/2025.08.28.672871

humanATAC-seq

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