Noura Maziak

The paper investigates how spatial and transcriptional dynamics at Cd4 and Cd8 loci influence T cell lineage choice in the thymus, revealing locus-specific chromatin environments that drive differentiation.

The paper identifies a conserved global control region for Hox gene regulation in annelids and shows convergent evolution of cluster-wide regulatory mechanisms in vertebrates and spiralians.

This study reconstitutes Drosophila chromatin architecture in a cell-free system, revealing spontaneous formation of long-range interactions and TADs.

This study shows that LBR and LAP2 tether heterochromatin to the nuclear periphery, and their loss disrupts genome homeostasis by repositioning heterochromatin and altering gene expression.

This study investigates how PRC2 depletion in AML affects epigenomic and transcriptional changes, revealing altered chromatin accessibility, H3K27me3 levels, and gene expression patterns that impact cell phenotype and treatment response.