Chemical activity profiling reveals how exposure to drugs or dietary compounds alters gut microbial biotransformation capacity
Hélène Bigonne, Shuhuan Zhai, Jacob S. Folz, Katherine A. Hurley, Aishwarya Murali, Franziska Maria Zickgraf, Hennicke Kamp, Bennard van Ravenzwaay, Georg Aichinger, Shana J. Sturla
The paper profiles chemical activities in rat gut microbiota to assess changes in biotransformation capacity after exposure to drugs and dietary compounds, finding significant alterations with certain antibiotics.
bioRxiv · May 20, 2025 · PreprintMicrobiology