Author

Qiongwei Ke

Guangdong Medical CollegeORCID 0000-0002-4273-4382Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1

Frequent Co-Authors

Feng CheniD· 2 shared Lili CuiiD· 2 shared Yuanhong SuniD· 2 shared Fubin Ma· 1 shared Huiyi Chen· 1 shared Ji Chen· 1 shared Liehua Deng· 1 shared Qin Haung· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersNeuroscience

Feng ChenORCID

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2 papers

Recent·Most cited

Phase separation drives SNARE complexes formation

Feng Chen, Qiongwei Ke, Sifan Feng, Huiyi Chen, Qin Haung, Fubin Ma, Yujie Cai, Ji Chen, Shengnan Li, Wenyan Wei, Yuanhong Sun, Xiao Jun Peng, Tong Lin, Xiaocong Sun, Liehua Deng, , Lili Cui

This study shows that phase separation drives SNARE complex formation and aggregation, with syntaxin1 non-IDRs necessary for this process, and identifies its role in recruiting synaptic vesicles.

bioRxiv · Mar 4, 2025 · PreprintNeuroscience

ApoE4 causes severe COVID-19 outcomes via downregulation of ACE2

Feng Chen, Yanting Chen, Qiongwei Ke, Yongxiang Wang, Xiongjin Chen, Xiaoping Peng, Yujie Cai, Shennan Li, Yuanhong Sun, Yao Ji, Yuling Jiang, Wenxian Wu, Yan Wang, Lili Cui

This study identifies ApoE4's role in worsening COVID-19 outcomes by downregulating ACE2 expression, reducing Ang II to Ang 1-7 conversion, and increasing SARS-CoV-2 infectivity.

bioRxiv · Sep 4, 2022 · PreprintNeuroscience