Feng Chen

This study shows that phase separation drives SNARE complex formation and aggregation, with syntaxin1 non-IDRs necessary for this process, and identifies its role in recruiting synaptic vesicles.

This study identifies ApoE4's role in worsening COVID-19 outcomes by downregulating ACE2 expression, reducing Ang II to Ang 1-7 conversion, and increasing SARS-CoV-2 infectivity.

The paper uses ultra-deep sequencing to assess oncogenic mutations in human hematopoietic stem and progenitor cells after CRISPR/Cas9 editing, finding no evidence of tumorigenic variants.

This paper presents a computational protocol to detect Candidate Phyla Radiation bacteria from metagenomic data, enabling the reconstruction of draft genomes and functional gene analysis.