Author

Jonathan R. Sillar

Hunter Medical Research InstituteORCID 0000-0002-4281-0402Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Anoop Kumar EnjetiiD· 2 shared Heather C. MurrayiD· 2 shared Nicole M. VerrillsiD· 2 shared Abdul MannaniD· 1 shared Alicia M. DouglasiD· 1 shared Ameha Seyoum WolduiD· 1 shared Andrew H. WeiiD· 1 shared Benjamin J. BuckleyiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersCancer Biology

Anoop Kumar EnjetiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 16, 2026

(E,E)-bisantrene suppresses MYC expression and displays anti-leukemic activity in acute myeloid leukemia

Heather C. Murray, Kasey Miller, Joshua S. Brzozowski…·Nicole M. Verrills

This study evaluates (E,E)-bisantrene's anti-leukemic activity in AML by showing it suppresses MYC expression and induces apoptosis across multiple models.

DOI 10.64898/2026.09.10.750805

humanproteomics

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Cancer BiologybioRxivPreprintJul 26, 2024

Adaptive resistance to FLT3 inhibitors is potentiated by ROS-driven DNA repair signalling

Dilana Elisabeth Staudt, Zacary P. Germon, Abdul Mannan…·Matthew D. Dun

This study identifies ATM-driven DNA repair and ROS addiction as mechanisms of resistance to FLT3 inhibitors in AML and shows ATM inhibition can overcome resistance in vitro and in vivo.

DOI 10.1101/2024.07.26.605229

humanbulk RNA-seq

𝕏 PostBluesky