Author

Keith P. Purpura

Weill Cornell MedicineORCID 0000-0002-4286-4603Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:database / resource· 1 Research Focus:dimensionality reduction· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1

Frequent Co-Authors

Jonathan BakeriD· 2 shared A Howard· 1 shared Alceste DeliiD· 1 shared Alexander L. GreeniD· 1 shared Andrea GuidoliniD· 1 shared Andrew SharottiD· 1 shared Ayana HellevikiD· 1 shared Bahar Baradaran· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersNeuroscience

Jonathan BakerORCID

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Author profile →

3 papers

Recent·Most cited

Scaling up polarization-sensitive optical coherence tomography to image the whole macaque brain

MariPen Yeatts, Nirupama Chinthalapati, Bahar Baradaran, Henry Heinks, Emily Liao, R. Huxford, Vasilis M Karlaftis, Taylor Grafft, Tanya K Casta, Ayana Hellevik, Pramod Kumar Pisharady, A Howard, Jan Zimmermann, Thomas Pengo, Jonathan Baker, , Taner Akkin

This paper develops a scalable PS-OCT system for whole-brain imaging in rhesus macaques, achieving high-resolution volumetric data with multi-terabyte datasets.

bioRxiv · Jun 15, 2026 · PreprintNeuroscience

A clinical grade neurostimulation implant for hierarchical control of physiological activity

Moaad Benjaber, Mayela Zamora, Robert Toth, John E. Fleming, Kei Landin, Victoria S. Marks, Rachel A. Crockett, Jae-Wook Ryou, Alceste Deli, Alexander L. Green, Rory J. Piper, Martin M. Tisdall, Derk‐Jan Dijk, Nicholas D. Schiff, Andrew Sharott, , Timothy J Denison

This paper introduces a clinical-grade neurostimulation implant that adapts its therapy based on time-of-day to improve closed-loop treatment of neurological disorders.

bioRxiv · Oct 21, 2025 · PreprintNeuroscience

Geometry of spiking patterns in early visual cortex: a Topological Data Analytic approach

Andrea Guidolin, Mathieu Desroches, Jonathan D. Victor, Keith P. Purpura, Serafim Rodrigues

The paper applies topological data analysis to spiking patterns in macaque visual cortex, revealing a low-dimensional geometric structure similar to Euclidean or hyperbolic spaces.

Journal of The Royal Society Interface · Nov 1, 2022Peer-reviewedNeuroscience