Eduarda Mota‐Silva

This study shows that ethanol-based fixation preserves immunomodulatory activity in MSC-derived microtissues, with functional potency increasing over 8 weeks of storage.

This study compares FLASH and conventional radiotherapy in melanoma-bearing and naive mice, finding FLASH reduces long-term tissue damage and systemic inflammation while maintaining tumor control.

The paper identifies genetic modifiers of Huntington's disease somatic CAG repeat instability using CRISPR-Cas9 in HD knock-in mice, revealing new therapeutic targets.

This study shows that targeting the MLH3 endonuclease domain reduces somatic CAG expansion in Huntington's disease models and patient cells.