Author
Jamia HamdardORCID 0000-0002-4318-8360Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Tree models on RDKit/Morgan features predict M.tb activity and MIC endpoints for drug-susceptible and resistant isolates, slightly beating pretrained embeddings; released as a Colab tool.
Jasdeep Singh, Raunak Jangid, Ankit Srivastava
AmyloCore-ML identifies amyloid-core regions in proteins using sequence-based predictors and protein language models, achieving high AUROC and AUPRC values.
Arpit Gupta, Priyanka Singh, Arpit Mehrotra…·Deepak Sharma
This study identifies penetratin as an inhibitor of α-synuclein aggregation and shows it improves locomotor function in Parkinson's disease mouse models.
Jasdeep Singh, Nasreen Z. Ehtesham, Syed Asad Rahman, Seyed E. Hasnain
The paper investigates the structural and functional impacts of mutations in the VUI-202012/01 SARS-CoV-2 variant, focusing on spike, ORF8, and nucleocapsid proteins, and their potential effects on immune evasion, transmission, and diagnostic assays.
Jasdeep Singh, H. Singh, Seyed E. Hasnain, Syed Asad Rahman
The paper analyzes 25k SARS-CoV-2 genomes to identify geographic mutations and their implications for host-pathogen interactions and vaccine efficacy.
Jasdeep Singh, Sudeshna Kar, Seyed E. Hasnain, Surajit Ganguly
The paper models SARS-CoV-2 ORF8's structural similarity to human complement factor 1's C3b binding site and predicts it competes with F1 for C3b binding, potentially causing unregulated complement activation.