The paper presents a proteomic dataset from rat cardiomyocytes treated with doxorubicin, identifying proteins regulated in young hearts and highlighting sex differences in cardiotoxicity.

bioRxiv · Apr 24, 2026 · PreprintMolecular Biology

Uncovering Shared and Tissue-Specific Molecular Adaptations to Intermittent Fasting in Liver, Brain, and Muscle

Yibo Fan, Senuri De Silva, Nishat I Tabassum, Xiangyuan Peng, Vernise JT Lim, Xiangru Cheng, Keshava K. Datta, Rohan G. T. Lowe, Terrance G. Johns, Mark P. Mattson, Suresh Mathivanan, Christopher Graeme Sobey, Eitan Okun, Yong Liu, Guobing Chen, , Thiruma Valavan Arumugam

This study identifies tissue-specific and shared molecular adaptations to intermittent fasting in liver, brain, and muscle using proteomics and transcriptomics.

eLife · Apr 17, 2026Peer-reviewedMolecular Biology

EPHA2-Ephrin-B1 cis-interaction supports self-renewal ability leading to recurrence of oral cancer.

Reshma Raj R, Nandini Datta, Soumya Krishnan U., Geetha Shanmugam, Jiss Maria Louis, Ravichandran Damodaran Jeyaram, Keshava K. Datta, Harsha Gowda, Meghna Sarkar, Madhumathy G Nair, Jyothy S. Prabhu, Hafsa Shabeer, P.G. Balagopal, A Thameem, Alan Jose, , Tessy Thomas Maliekal

This study identifies Ephrin-B1-EPHA2 cis-interaction as a driver of oral cancer self-renewal and recurrence, validated through proteomics, biochemical assays, and clinical data.

Cell Communication and Signaling · Mar 11, 2026Peer-reviewedCancer Biology

Proteome-wide characterization and biomarker identification of intracranial aneurysm

Tanavi Sharma, Keshava K. Datta, Munish Kumar, Gourav Dey, Aafaque Ahmad Khan, Kiran Kumar Mangalaparthi, Poonam Saharan, Shobia Chinnapparaj, Ashish Aggarwal, Navneet Singla, Sujata Ghosh, Amit Kumar Rawat, Sivashanmugam Dhandapani, Pravin Salunke, Rajesh Chhabra, , Hemant Bhagat

This study identifies potential biomarkers for intracranial aneurysm subtypes through proteomic analysis of tissue and serum samples.

bioRxiv · Aug 9, 2019 · PreprintNeuroscience