Guobing Chen

This study shows that parental intermittent fasting induces intergenerational molecular changes in the brain, affecting sensory pathways and sex-dependent gene expression in offspring.

This study identifies tissue-specific and shared molecular adaptations to intermittent fasting in liver, brain, and muscle using proteomics and transcriptomics.

This study shows intermittent fasting changes chromatin accessibility and gene expression in brain and muscle tissues of mice, affecting metabolic and functional pathways.

The paper shows NAD+ and EVA1-C regulate alternative splicing in tauopathies, affecting protein interactions and disease progression, suggesting therapeutic potential for AD.

This paper develops a 15-gene prognostic signature, PRSM, to predict platinum response in ovarian cancer, identifying TFAP2B as a key contributor to resistance.