Molecular BiologybioRxivPreprint
G9a/GLP methyltransferases inhibit autophagy by methylation-mediated ATG12 protein degradation
Changhoon Kim, Kyung‐Tae Park, Shinyeong Ju…·Sang‐Hun Lee
This study shows G9a/GLP methyltransferases inhibit autophagy by methylating and degrading ATG12, but their degradation under stress allows ATG12 accumulation and autophagy activation.
6 citations