Cheolju Lee

The anatomical compartment defines distinct immune remodeling within human visceral adipose tissue during aging

The paper examines age-related immune changes in different visceral adipose tissue depots, finding depot-specific immune remodeling linked to adjacent organ function.

Implementing N-terminomics and machine learning to probe in vivo Nt-arginylation

This study identifies in vivo Nt-arginylation sites using N-terminomics combined with machine learning, revealing increased arginylation under UPR stress and its localization across organelles.

RNA dicing regulates the expression of an oncogenic JAK1 isoform

The paper shows RNA dicing produces an oncogenic JAK1 isoform, affecting cell proliferation and tumorigenesis, and highlights its therapeutic implications.

Naa12 compensates for Naa10 in mice in the amino-terminal acetylation pathway

The paper identifies Naa12 as a compensatory N-terminal acetyltransferase that rescues Naa10 deficiency in mice, revealing its role in amino-terminal acetylation.

G9a/GLP methyltransferases inhibit autophagy by methylation-mediated ATG12 protein degradation

This study shows G9a/GLP methyltransferases inhibit autophagy by methylating and degrading ATG12, but their degradation under stress allows ATG12 accumulation and autophagy activation.