Author

Xiaopu Zhang

King's College LondonORCID 0000-0002-4345-3443Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:benchmarking· 1 Assay:DNA methylation· 1 Research Focus:GWAS / association mapping· 1 Assay:imaging· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Jordana T. BelliD· 3 shared Andrew WongiD· 1 shared Daniel A LevyiD· 1 shared Dorret Irene BoomsmaiD· 1 shared İdil YetiD· 1 shared Jenny van DongeniD· 1 shared Jiantao MaiD· 1 shared Josine L. MiniD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersGenetics

Jordana T. BellORCID

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3 papers

Recent·Most cited

Genetic Impacts on Variability of Body Fat Distribution Uncover Gene-Environment and Gene-Gene Interactions

Xiaopu Zhang, Roby Joehanes, Jiantao Ma, Oliver Pain, Daniel A Levy, Kenneth E. Westerman, Jordana T. Bell

The paper identifies variance QTLs (vQTLs) and gene-environment interactions for body fat distribution using UK Biobank MRI and genetic data, with replication in external cohorts.

bioRxiv · Apr 2, 2026 · PreprintGenetics

Genetic impacts on within-pair DNA methylation variance in monozygotic twins capture gene-environment interactions and cell-type effects

Xiaopu Zhang, İdil Yet, Sergio Villicaña, Juan Castillo Fernandez, Massimo Mangino, Jouke‐Jan Hottenga, Pei-Chien Tsai, Josine L. Min, Mario Falchi, Andrew Wong, Dorret Irene Boomsma, Ken K. Ong, Jenny van Dongen, Jordana T. Bell

The paper identifies vmeQTLs for blood DNA methylation variance in MZ twins, showing gene-environment interactions and cell-type effects relevant to immune disease.

Genome biology · Feb 7, 2026Peer-reviewedGenetics

Detecting genetic effects on phenotype variability to capture gene-by-environment interactions: a systematic method comparison

Xiaopu Zhang, Jordana T. Bell

This paper compares methods for detecting genetic variants affecting phenotypic variance under gene-environment interactions and identifies optimal approaches for different exposure types.

G3 Genes Genomes Genetics · Jan 30, 2024Peer-reviewedGenetics