Pei-Chien Tsai

The paper identifies vmeQTLs for blood DNA methylation variance in MZ twins, showing gene-environment interactions and cell-type effects relevant to immune disease.

The paper identifies genetic impacts on DNA methylation across 724,499 CpGs in blood samples, revealing co-localisations with disease traits and regulatory mechanisms.

This study identifies DNA methylation sites associated with coffee and tea consumption using EWAS, finding potential links to fatty liver disease through PHGDH expression.

This study identifies 137 genome-wide significant loci associated with DNA methylation biomarkers of ageing using DNAm and SNP data from over 41,000 individuals.

This study quantifies XCI skewing in female twins across tissues, showing age- and tissue-specific heritability and associations with smoking in older females.

This study identifies nine novel DNA methylation sites associated with fasting glucose and insulin levels by integrating cross-omics data from multiple cohorts.

This study identifies DNA methylation changes in blood and tissue samples associated with periodontal disease in older female twins.

This study identifies smoking-associated DNA methylation and gene expression changes in adipose tissue and links some to cardio-metabolic health outcomes.

The paper quantifies age-related changes in gene expression levels, splicing, and variance across tissues and identifies environmental and genetic influences on these changes in a twin cohort.

This study identifies genetic variants associated with epigenetic age acceleration and shows TERT's role in regulating the DNA methylation clock.