Topical administration of novel FKBP12 ligand MP-004 improves retinal function and structure in retinitis pigmentosa models.
Araceli Lara-López, Klaudia González-Imaz, María Rodríguez-Hidalgo, Miren Sarasola-Gastesi, Leire Escudero-Arrarás, Santiago Milla Navarro, Pedro de la Villa, Maialen Sagartzazu‐Aizpurua, Jose Ignacio Miranda, Jesús María Aizpurua, Adolfo López de Munaín, Ainara Vallejo‐Illarramendi, Javier Ruiz‐Ederra
This study evaluates MP-004, a novel FKBP12 ligand, showing improved retinal function and structure in retinitis pigmentosa models through protection against oxidative stress and cell death.
Investigative Ophthalmology & Visual Science · Mar 26, 2025Peer-reviewedNeuroscience