Assessment of the pharmacological and safety profile of the small molecule MP-004 after topical eye drops administration
Araceli Lara-López, María Rodríguez-Hidalgo, Miren Sarasola-Gastesi, Klaudia González-Imaz, Julián Zayas, Maialen Sagartzazu‐Aizpurua, Jose Ignacio Miranda, Ana Espinosa, Adolfo López de Munain, Jesús María Aizpurua, Francisco Javier Gil-Bea, Ainara Vallejo‐Illarramendi, Javier Ruiz‐Ederra
This study evaluates the pharmacological and safety profile of MP-004 after topical eye drops in mice, rabbits, and pigs, showing effective retinal concentrations and minimal systemic exposure.
bioRxiv · Oct 9, 2025 · PreprintPharmacology & Toxicology