María Rodríguez-Hidalgo

This study shows that loss of TDP-43 causes premature aging in skeletal muscle stem cells, reducing their regenerative capacity and leading to muscle degeneration.

The paper identifies early ALS-related lipid changes in presymptomatic SOD1G93A mice using lipid imaging mass spectrometry, showing sex-dependent and fiber-type-specific alterations detectable before symptoms.

This study investigates the effects of systemic FOXO1 inhibition in hSOD1G93A mice, finding limited therapeutic benefit in modifying disease progression or muscle pathology.

This study evaluates the pharmacological and safety profile of MP-004 after topical eye drops in mice, rabbits, and pigs, showing effective retinal concentrations and minimal systemic exposure.

This study develops a novel in vitro protocol to generate lymphatic endothelial progenitor cells from stromal vascular fraction, showing robust differentiation and scalability.

This study evaluates MP-004, a novel FKBP12 ligand, showing improved retinal function and structure in retinitis pigmentosa models through protection against oxidative stress and cell death.