Boris Vandemoortele

Lemonite: identification of regulatory metabolites through data-driven, interpretable integration of transcriptomics and metabolomics data

Lemonite integrates transcriptomics and metabolomics data to identify regulatory metabolites acting on gene modules in glioblastoma and inflammatory bowel disease.

Focus on the edges: a biomolecular network of histone PTMs, metabolites and proteins unveils functional entanglement in AML

The paper constructs a multi-omics biomolecular network in AML using proteins, metabolites, and histone PTMs to reveal functional entanglement between biomolecules.

Comparison of different computational frameworks for metabolic modeling from single-cell transcriptomics data in glioblastoma

The paper compares three computational methods to infer metabolism from single-cell transcriptomics data in glioblastoma, finding tumor-associated macrophages as metabolically dominant.

Evaluation of single-sample network inference methods for precision oncology

This study evaluates single-sample network inference methods for cancer subtyping using bulk RNA-seq data from cancer cell lines.