ImmunologyeLifePeer-reviewed
Reprogramming of host energy metabolism mediated by the TNF-iNOS-HIF-1alpha axis plays a key role in host resistance to Plasmodium infection
Kely Catarine Matteucci, Nathalia PS Leite, Patricia Aparecida de Assis…·Ricardo T. Gazzinelli
The paper shows that the TNF-iNOS-HIF-1alpha axis drives glycolysis in monocytes, enhancing host resistance to Plasmodium infection and sickness behavior.
4 citations