Author

Wei Zhang

Central South UniversityORCID 0000-0002-4375-0368Unclaimed ORCID profile · follow to get notified of new preprints

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Wei Zhang38 papers · Chinese Academy of Sciences

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Alyssa B. FanelliiD· 1 shared Amy D. Westerling-BuiiD· 1 shared Dongbiao Liu· 1 shared Eva Maria FastiD· 1 shared G. MalojciciD· 1 shared Grinal M. Corriea· 1 shared Hien G. HoangiD· 1 shared Jean-Christophe HarmangeiD· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alyssa B. FanelliORCID

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2 papers

Recent·Most cited

The role of miR-31-5p in the development of intervertebral disk degeneration and its therapeutic potential

Yong Zhou, Jiqing Su, Mingsi Deng, Wei Zhang, Dongbiao Liu, Zhengguang Wang

This study identifies miR-31-5p as a key regulator of intervertebral disc degeneration, showing it promotes cell proliferation, inhibits apoptosis, and reduces matrix degradation by targeting the SDF-1/CXCR7 axis.

Frontiers in Cell and Developmental Biology · Mar 18, 2021Peer-reviewedMolecular Biology

A translational kidney organoid system bolsters human relevance of clinical development candidate

Amy D. Westerling-Bui, Thomas W. Soare, Srinivasan P Venkatachalan, Michael DeRan, Eva Maria Fast, Alyssa B. Fanelli, Sergii Kyrychenko, Hien G. Hoang, Grinal M. Corriea, Wei Zhang, Maolin Yu, Matthew H. Daniels, G. Malojcic, Xin-Ru Pan-Zhou, Mark W. Ledeboer, , Peter H. Mundel

The paper develops a high-throughput human kidney organoid platform for drug screening, validated by scRNA-Seq and showing protective effects of CsA and GFB-887 against kidney injury.

bioRxiv · Dec 30, 2019 · PreprintGenomics