Sebastián Contreras-Riquelme

Organ-level Gene Regulatory Network models enable the identification of central transcription factors in Solanum lycopersicum

The paper constructs organ-level gene regulatory networks in tomato using RNA-seq data and validates them with DAP-seq, identifying key and novel transcription factors involved in fruit ripening and ABA response.

Transcriptional and Histone acetylation changes associated with CRE elements expose key factors governing the regulatory circuit in early stage of Huntington's disease models.

Automated generation of context-specific Gene Regulatory Networks with a weighted approach in D. melanogaster

The paper introduces Fly T-WEoN, a tool for generating context-specific Gene Regulatory Networks in D. melanogaster by filtering known regulations using epigenomic data.