Kathleen A. Beeson

Altered hippocampal activation in seizure-prone CACNA2D2 knockout mice

This study examines hippocampal activation and histopathological changes in CACNA2D2 knockout mice, finding altered functional activity without significant structural changes associated with seizure susceptibility.

α2δ-2 is Required for Depolarization-induced Suppression of Excitation in Purkinje cells

This study shows that α2δ-2 is essential for coupling calcium entry to two postsynaptic signals in Purkinje cells.

α2δ-2 protein controls structure and function at the cerebellar climbing fiber synapse

This study examines the role of α2δ-2 protein in cerebellar climbing fiber synapses using Cacna2d2 knockout mice, revealing structural and functional changes in synaptic transmission and their impact on ataxia.