Author

Zhanshan Sam Ma

Harvard UniversityORCID 0000-0002-4397-2630Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:ecology & biodiversity· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:metagenomics· 1

Frequent Co-Authors

Aaron M. EllisoniD· 1 shared Jiali LiiD· 1 shared Li YaoiD· 1 shared Lianwei LiiD· 1 shared Siling LiuiD· 1 shared Zhongyu ZhangiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 10 mutual co-author links

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1 shared paperEcology

Aaron M. EllisonORCID

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2 papers

Recent·Most cited

Estimation, testing, and inference of network heterogeneity

Zhanshan Sam Ma, Aaron M. Ellison

This paper introduces a methodology for estimating, testing, and inferring network heterogeneity in ecological systems using the Earth Microbiome Project dataset.

bioRxiv · May 11, 2026 · PreprintEcology

ADAM10- and presenilin 1/γ-secretase-dependent cleavage of PTPRT mitigates neurodegeneration of Alzheimer's disease

Siling Liu, Zhongyu Zhang, Lianwei Li, Li Yao, Zhanshan Sam Ma, Jiali Li

The paper identifies that cleavage of PTPRT by ADAM10 and presenilin 1/γ-secretase produces PICD, which reduces neurodegeneration in Alzheimer's disease by modulating STAT3 and Aβ.

bioRxiv · Jan 11, 2021 · PreprintNeuroscience