Author

Siling Liu

Kunming Institute of ZoologyORCID 0000-0002-0271-1637Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Jiali LiiD· 2 shared Baizhen Zhao· 1 shared Hei‐Man ChowiD· 1 shared Jacquelyne Ka‐Li SuniD· 1 shared Jie ShiiD· 1 shared Kaiyu XuiD· 1 shared Karl HerrupiD· 1 shared Li YaoiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMolecular Biology

Jiali LiORCID

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2 papers

Recent·Most cited

The mtDNA-derived lncMtDloop promotes mitochondrial homeostasis maintenance and implications in AD

Wandi Xiong, Kaiyu Xu, Jacquelyne Ka‐Li Sun, Siling Liu, Baizhen Zhao, Jie Shi, Karl Herrup, Hei‐Man Chow, Lin Lü, Jiali Li

This study identifies lncMtDloop as a regulator of mitochondrial homeostasis, showing reduced expression in AD and improved pathology with its overexpression.

bioRxiv · Oct 30, 2023 · PreprintMolecular Biology

ADAM10- and presenilin 1/γ-secretase-dependent cleavage of PTPRT mitigates neurodegeneration of Alzheimer's disease

Siling Liu, Zhongyu Zhang, Lianwei Li, Li Yao, Zhanshan Sam Ma, Jiali Li

The paper identifies that cleavage of PTPRT by ADAM10 and presenilin 1/γ-secretase produces PICD, which reduces neurodegeneration in Alzheimer's disease by modulating STAT3 and Aβ.

bioRxiv · Jan 11, 2021 · PreprintNeuroscience