NeuroscienceCell Death and DiseasePeer-reviewed
Abnormal neuronal and synaptic morphology in Down syndrome brains reproduces in human isogenic cellular models
Ante Plećaš, Gillian Gough, Danka Grčević…·Ivan Alić
This study shows that trisomy 21 in human isogenic iPSC-derived neurons leads to abnormal neuronal and synaptic morphology, similar to findings in human brain tissue.
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