Author

Ante Plećaš

University of ZagrebORCID 0000-0001-5839-889XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Aoife MurrayiD· 2 shared Dean NižetićiD· 2 shared Ivan AlićiD· 2 shared Danka GrčevićiD· 1 shared Dinko MitrečićiD· 1 shared Gillian GoughiD· 1 shared Hanna JackowiakiD· 1 shared Hyo Jung KangiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Aoife MurrayORCID

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2 papers

Recent·Most cited

NeuroscienceCell Death and DiseasePeer-reviewedJun 10, 2026

Abnormal neuronal and synaptic morphology in Down syndrome brains reproduces in human isogenic cellular models

Ante Plećaš, Gillian Gough, Danka Grčević…·Ivan Alić

This study shows that trisomy 21 in human isogenic iPSC-derived neurons leads to abnormal neuronal and synaptic morphology, similar to findings in human brain tissue.

1 citationtop 4%

humanspatial transcriptomics

𝕏 PostBluesky

NeuroscienceNature CommunicationsPeer-reviewedJan 22, 2026

Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome

Saad B. Hannan, Ivan Alić, Aoife Murray…·Trevor G. Smart

This study shows that trisomy 21 impairs cortical circuit development by disrupting synaptic connectivity and intrinsic membrane properties in neurons.

3 citationstop 1%

humanelectronic health records

𝕏 PostBluesky