Author

Kazumi Kasakura

Tokyo University of ScienceORCID 0000-0002-4412-3737Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Chiharu NishiyamaiD· 3 shared Kazuki NagataiD· 3 shared Kenta IshiiiD· 3 shared Naoto ItoiD· 3 shared Ko OkumuraiD· 1 shared Mariko Inoue· 1 shared Mutsuko HaraiD· 1 shared Niya Yamashita· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersImmunology

Chiharu NishiyamaORCID

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3 papers

Recent·Most cited

ImmunologyAllergology InternationalPeer-reviewedMay 22, 2025

The role of GATA2 in the expression of the soluble decoy receptor ST2/IL1RL1 in human and mouse mast cells

Kazuki Nagata, Kazumi Kasakura, Kenta Ishii…·Chiharu Nishiyama

This study identifies GATA2 as a key regulator of sST2 expression in mast cells through chromosomal conformational changes.

DOI 10.1016/j.alit.2025.04.004

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Molecular BiologybioRxivPreprintFeb 10, 2025

PU.1 and TGF-β signaling transactivate CD103 expression in mast cells and dendritic cells: Opposite roles of GATA2 in the expression of mucosal mast cell-specific genes

Kenta Ishii, Kazuki Nagata, Niya Yamashita…·Chiharu Nishiyama

The paper investigates the transcriptional regulation of CD103 in mast cells and dendritic cells, showing that PU.1 transactivates CD103 expression while GATA2 represses it.

DOI 10.1101/2025.02.10.637371

mousebulk RNA-seq

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ImmunologyFEBS LettersPeer-reviewedDec 11, 2024

Roles of C/EBPα, GATA2, TGF-β-signaling, and epigenetic regulation in the expression of basophil-specific protease genes

Ryotaro Tojima, Kazuki Nagata, Naoto Ito…·Chiharu Nishiyama

The paper investigates the transcriptional regulation of basophil-specific protease genes Mcpt8 and Mcpt11, identifying C/EBPα, GATA2, TGF-β signaling, and epigenetic factors as key regulators.

2 citations

experimental assaycell type annotation

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