Acute E2/P4 loss compromises the biology and function of neurogenic niches during a vulnerable female aging period
Sree Vani Poorna Pillutla, Maddy J. Skoda, Atsushi Ishii…·Lalitha Madhavan
This study shows that loss of estradiol and progesterone in female rats at 9 months of age reduces neurogenesis and behavioral function, earlier than age-related declines at 14 months.