Caroline Delandre

The paper shows that GAL4 driver expression in Drosophila declines rapidly with age, with some drivers losing activity within 30 days.

This paper develops and validates an optogenetic tool, PiGM-Iq, to inhibit Gq signaling and demonstrates its effects on behavior, axon guidance, and neuronal development in multiple organisms.

The paper identifies eight chromatin states in Drosophila that segregate the genome into developmental and housekeeping roles through chromatin protein and histone mark associations.

This study identifies CUX2 and CASP variants in temporal lobe epilepsy patients and shows they increase seizure susceptibility and excitatory synaptic transmission.

The paper introduces FlyORF-TaDa, a system that rapidly generates transgenic Drosophila lines for cell-type specific profiling of protein-DNA interactions using existing FlyORF libraries.

The paper identifies Psi as a repressor of developmental pathways that promotes Drosophila wing growth by both activating Myc and repressing growth inhibitors.

The paper introduces new TaDa vectors that enable simultaneous profiling of protein-DNA interactions and visualization of expression domains using membrane-bound GFP or mCherry labels.