Jakko van Ingen

Analytical concordance of targeted next-generation sequencing and whole-genome sequencing for Mycobacterium tuberculosis drug resistance and lineage determination in West Java, Indonesia

This study compares targeted next-generation sequencing (tNGS) and whole-genome sequencing (WGS) for detecting drug resistance and lineage in Mycobacterium tuberculosis samples, finding high concordance for most drugs but some discrepancies in mutation detection and lineage resolution.

Activity of a three-phage combination against Mycobacterium tuberculosis in disease-relevant conditions

This study evaluates a three-phage combination's activity against Mycobacterium tuberculosis under hypoxic, acidic, and stationary-phase conditions, finding that phages require replicating bacteria for lytic activity.

A new stress-response pathway in Mycobacterium tuberculosis

This study identifies a new stress-response pathway in Mycobacterium tuberculosis that produces GABA-trehalose under hypoxia and immune stress.

An optimized protocol for dual RNA-Seq of human macrophages infected with Mycobacterium avium

This paper presents an optimized dual RNA-Seq protocol for human macrophages infected with Mycobacterium avium to better study host-pathogen interactions.