Denis Le Bihan

This paper shows that BIN1 overexpression in mice leads to early structural and functional impairments in hippocampal pathways associated with Alzheimer's disease, independent of A-beta changes.

This study examines how inhibiting aquaporin-4 channels affects BOLD and diffusion fMRI responses in rat visual cortex, showing increased BOLD amplitude but no change in diffusion responses.

The paper uses diffusion MRI to show that inhibiting AQP4 reduces the Sindex and increases sADC in mouse brain regions, indicating astrocyte activity changes.