Molecular BiologybioRxivPreprint
Reversal of ageing- and injury-induced vision loss by Tet-dependent epigenetic reprogramming
Yuancheng Ryan Lu, Anitha Krishnan, Benedikt Brommer…·David A. Sinclair
This paper demonstrates that epigenetic reprogramming using OSK genes can reverse age-related and injury-induced vision loss in mice by resetting DNA methylation patterns and promoting axon regeneration.
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