Author

Xiangsong Feng

Columbia University Irving Medical CenterORCID 0000-0002-4474-2351Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:cryo-EM· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Joachim FrankiD· 2 shared Priyanka GargiD· 1 shared Swastik DeiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

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3 top collaborators · 3 mutual co-author links

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2 shared papersBiophysics

Joachim FrankORCID

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2 papers

Recent·Most cited

BiophysicsJournal of Structural BiologyPeer-reviewedJul 4, 2025

Passage through micro-sprayer increases functional activity-implications for activity assays in time-resolved cryo-EM

Priyanka Garg, Xiangsong Feng, Swastik De, Joachim Frank

The paper assesses a micro-sprayer assay for ribosome functional activity, finding increased GFP production due to mechanical agitation, with implications for time-resolved cryo-EM experiments.

1 citation

proteomicsexperimental assay

𝕏 PostBluesky

BiophysicsBIO-PROTOCOLPeer-reviewedJan 1, 2025

Time-resolved cryo-EM (TRCEM) sample preparation using a PDMS-based microfluidic chip assembly

Xiangsong Feng, Joachim Frank

This paper introduces a PDMS-based microfluidic chip for time-resolved cryo-EM sample preparation, enabling structural and kinetic studies of biomolecular reactions in the 10-1000 ms time range.

6 citations

cryo-EMexperimental assay

𝕏 PostBluesky