Swastik De

Structural Studies of Nedicistrovirus IRES-Driven, Initiation Factor-independent Translation Shed Light on Key Steps of Eukaryotic Translation Elongation

The paper determines high-resolution structures of NediV IRES-mediated translation initiation complexes and their transition to elongation, revealing structural changes and interactions during viral translation.

Structures of Naked Mole-Rat, Tuco-Tuco, and Guinea Pig Ribosomes: Is rRNA Fragmentation Linked to Translational Fidelity?

The paper compares ribosome structures of naked mole-rats, tuco-tucos, and guinea pigs, finding fragmented 28S rRNA in the former with potential links to high translational fidelity.

Passage through micro-sprayer increases functional activity-implications for activity assays in time-resolved cryo-EM

The paper assesses a micro-sprayer assay for ribosome functional activity, finding increased GFP production due to mechanical agitation, with implications for time-resolved cryo-EM experiments.

Inconsistencies in the published rabbit ribosomal rRNAs: a proposal for uniformity in sequence and site numbering

The paper identifies inconsistencies in rabbit ribosomal rRNA sequences and proposes using the Broad Institute's genome sequence to standardize numbering and improve model consistency.

Molecular architecture of 40S initiation complexes on the Hepatitis C virus IRES: from ribosomal attachment to eIF5B-mediated reorientation of initiator tRNA

The paper presents cryo-EM structures of Hepatitis C virus IRES initiation complexes, revealing conformational changes during translation initiation.