Author

Elena Anahí Bignante

Consejo Nacional de Investigaciones Científicas y TécnicasORCID 0000-0002-4485-6375Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alfredo LorenzoiD· 1 shared Carlos Leandro FreitesiD· 1 shared Gonzalo QuassolloiD· 1 shared M. Florencia SáncheziD· 1 shared Magdalena AntoninoiD· 1 shared Paula Marmo· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperNeuroscience

Alfredo LorenzoORCID

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1 paper

Recent·Most cited

Aβ promotes amyloidogenic processing of APP through a Go/Gβγ signaling

Magdalena Antonino, Paula Marmo, Carlos Leandro Freites, Gonzalo Quassollo, M. Florencia Sánchez, Alfredo Lorenzo, Elena Anahí Bignante

This study identifies a feed-forward mechanism where Aβ promotes APP processing via Go/Gβγ signaling, enhancing Aβ production and suggesting gallein as a potential therapeutic target.

bioRxiv · Mar 10, 2021 · PreprintNeuroscience